[CAFÉ] Fwd: New BASF unmet needs in Health and Nutrition and Enzyme technologies

[Deborah Pagliaccia]

Thanks Jim!

---------- Forwarded message ---------
From: Jim Llano <james.llano at ucr.edu>
Date: Thu, Oct 29, 2020 at 7:55 AM
Subject: New BASF unmet needs in Health and Nutrition and Enzyme
technologies
To: Deborah Pagliaccia <deborahp at ucr.edu>, Norman Ellstrand <
ellstrand at ucr.edu>


Dear Deborah and Norm,



Some of the below BASF “unmet needs” fall into areas of food and vitamins,
and enzyme technologies which may resonate with the CAFÉ community.



Thanks, Jim



*From:* Christopher D Hewitt [mailto:christopher.d.hewitt at basf.com]
*Sent:* Thursday, October 29, 2020 6:24 AM
*Subject:* New BASF unmet needs in Health and Nutrition and Enzyme
technologies



Hello



BASF has some new unmet needs in these areas, as listed below.



Please reach out to me if you have unique competence that could help us to
address these needs or have specific questions.



Leveraging synthetic biochemistry / cell free technologies for
protein/enzyme production, strain optimization for heterologous expression
and predictability of expression

Novel In silico models for predicting expressibility of large proteins /
enzymes in microorganisms

Novel protein design approaches to predict improvement of enzyme molecule
(substrate specificity, catalytic efficiency, temperature and biophysical
stability in process/formulations)

Novel technologies for early stage prediction of fermentation process
robustness, and scalability

Novel technologies for enzyme discovery

Novel approaches for HTP automation and digitalization capabilities and
workflows

Replacement of porcine gelatin for tablets (e.g. biobased collagen)

Crosslinking of alginate without viscosity issues: improving loading
capacity

Use of chitosan for encapsulations - challenge is loading capacity and
performance

How to make powders flow without nanoflow aids

New effective all-natural antioxidants

Interactions of vitamins/carotenoids with natural polymers such as
(partially) hydolyzed proteins, different starch types etc

New formulations improving bioavailability/ bioaccessibility of vitamins,
carotenoids and other health ingredients

How to achieve performance level of modified starches with non-modified
versions/mixtures

Protein, hydrolysates and other natural polymers as emulsifiers in food

Alternative natural foaming agents

Egg substitution

New formats of micronutrient application in food fortification

New highly cost-effective formulation technologies

Improvements in spray-drying (getting larger particles, less energy needed
etc)

Spray-drying with assistance of electrical fields

Low energy process for emulsifier production

A more sustainable cost-effective production of food grade Vitamin A and E
compared with usual synthetic routes (e.g biobased intermediates in the
process or final product)

Cost effective regulatory favorable natural ingredients (e.g. Vitamin B5,
Vitamin B12, Vitamin D3, Carotenoids)

Avoiding formation of contaminants in production process and/or subsequent
reduction (e.g. 3-MCPD, benzene, MOSH, MOAH etc)





Kind regards
* Dr. Chris Hewitt, F.R.S.C.*
Innovation Network Manager



Phone: +1 734 324-6149, Mobile: +1 724 931-9069, Fax: +1 289 360-6001,
Email: christopher.d.hewitt at basf.com
Postal Address: BASF Corporation, 2 TW Alexander Drive, 27713 Research
Triangle Park, USA












-- 
Deborah Pagliaccia, Ph.D.
Professional Researcher, Department of  Microbiology and Plant Pathology
Managing Director, California Agriculture and Food Enterprise - CAFÉ
<http://cafe.ucr.edu/>
UCR Global Food Initiative <http://globalfood.ucr.edu/> Co-Chair
University of California
Riverside, CA 92521

California Citrus Nursery Society <http://ccns.info/> CCNS Executive
Director
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <https://lists.ucr.edu/pipermail/cafe/attachments/20201029/c9ca2fc2/attachment.html>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image001.png
Type: image/png
Size: 2015 bytes
Desc: not available
URL: <https://lists.ucr.edu/pipermail/cafe/attachments/20201029/c9ca2fc2/attachment.png>