[IIGB_All] Exciting news regarding the enhanced capabilities of the IIGB Multiomics

[Katayoon Dehesh]

Dear colleagues,

I am excited to share some exciting news regarding the enhanced capabilities of the IIGB Multiomics Core Facility at our campus. Our facility now offers advanced services in metabolomics, proteomics, data analyses, genomics, and bioinformatics (see below).

This expansion represents a significant milestone for our research community. Thanks to the diligent and hard work of the core staff, the cores are now able to provide researchers across disciplines with access to cutting-edge technologies and expertise, empowering them to delve deeper into their scientific inquiries and accelerate discoveries.

The inclusion of metabolomics, proteomics, genomics, and bioinformatics services signifies our commitment to providing comprehensive support for diverse research projects. Whether you are studying metabolic pathways, protein interactions, genomic variations, or complex data analysis, our facility is equipped to meet your needs.

I encourage you to explore the expanded services offered by the IIGB Multiomics Core Facility and leverage these resources to advance your research endeavors. Together, we can continue to push the boundaries of scientific exploration and innovation.
Be powerful
Katie

Metabolomics:
Measurement of volatile compounds (Headspace-SPME).
Upgraded GC-MS platform in 2023 with Headspace Solid Phase Micro Extraction capabilities, boosting analytical capabilities for volatile compounds.
Metabolite imaging (MALDI-TOF).
Acquired new MS imaging source for the Synapt G2si in December 2023, enabling MS imaging experiments for metabolite abundance mapping in biological and synthetic sample sections.
Proteomics:
Protein Post-Translational Modification (PTM) Analysis
High Selectivity and Sensitivity Targeted Proteomics
Data-Independent Acquisition (DIA) Proteomics (Opening Soon)
Protein Purification
Genomics:
Acquisition of advanced instruments including Illumina NextSeq 2000 Sequencing Platform, Oxford Nanopore MinION and Flongle Sequencing Platforms, and more.
Bioinformatics:
Addition of single-cell RNA-seq analysis to services, alongside RNA-seq and ChIP-seq.
Note: Open bioinformatics office hours (2-3 PM Daily via Calendly appt).
Data Analysis:
Introduced Parallel Fold-Change Analysis method, supported by ShowMEPATH tool, automating pathway generation and facilitating large-scale comparisons in biological research. ShowMEPATH expedites analysis of metabolite or transcript changes, offering efficient insights into complex dataset patterns. Its automation manages expanding biological data scale, while the Parallel Fold-Change Plot enhances interpretation of complex dataset relationships. ShowMEPATH ensures meaningful interpretation in complex biological comparisons.

Katayoon (Katie) Dehesh
Director, Institute for Integrative Genome Biology, Distinguished Professor
Ernst and Helen Leibacher Endowed Chair in Botany and Plant Sciences
University of California, Riverside, CA 92521
Phone: (951) 827-6370;  Fax: (951) 827-5155


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