[Allgsacstudents] CMDB281: SEMINAR IN MOLECULAR CELL BIOLOGY Spring 2025

[allgsacstudents at lists.ucr.edu]

CMDB281:  SEMINAR IN

*MOLECULAR CELL BIOLOGY*

*Spring 2025*



*Cell and Molecular Basis of *

*Oxidative Stress-induced mitochondrial dysfunction, cell death and
inflammation *



*Instructor: Dr. M. Martins-Green*

*Department of Molecular, Cell and System Biology*





The maintenance of biological redox potential *in vivo* is vital for the
proper function and integrity of cells, tissues, organs and physiological
systems. Recent evidence showing the destructive roles of excess oxidative
stress in mitochondrial function, cell death and inflammation is mounting
resulting in imbalanced redox causing diseases such as diabetes,
atherosclerosis and impaired/chronic wounds. In this class we will learn
about the mechanisms by which oxidative stress, mitochondrial dysfunction
and inflammation play in destroying the body at the cellular and molecular
level leading to disease. This class will help us look at disease in a
different light, and see that in most cases disease is caused by excess
levels of oxidative stress.



*Organizational meeting on Wednesday the 8th of April at 12-1 pm in BSB
2101.  *At this meeting I will discuss the mechanics of the course and my
expectations and will answer any questions/concerns you might have.  We
will also discuss the best time for the class and potential subtopics you
can choose from the general topic for your presentation.   Alternatively,
you can suggest your own topic so long as it is within the subject of the
course.



*For questions: *Dr. Martins-Green

                         2117 Biological Sciences
Building
                email: manuela.martins at ucr.edu
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