<div dir="auto">Hi all, </div><div dir="auto"><br></div><div dir="auto">PFA</div><div dir="auto"><br></div><div dir="auto">Best, </div><div dir="auto">Navaira</div><div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">---------- Forwarded message ---------<br>From: <strong class="gmail_sendername" dir="auto">Mark Alber</strong> <span dir="auto"><<a href="mailto:malber@ucr.edu">malber@ucr.edu</a>></span><br>Date: Mon, Nov 4, 2024 at 3:54 PM<br>Subject: Applied Mathematics Colloquium: Dr. Eric Cytrynbaum, Wed Nov 06<br>To: Ke Zhang <<a href="mailto:kzhan153@ucr.edu">kzhan153@ucr.edu</a>>, Navaira Sherwani <<a href="mailto:nsher012@ucr.edu">nsher012@ucr.edu</a>>, Ruoxi Zhao <<a href="mailto:rzhao065@ucr.edu">rzhao065@ucr.edu</a>>, Xin Xiang <<a href="mailto:xxian002@ucr.edu">xxian002@ucr.edu</a>>, Rose Johnson-Leiva <<a href="mailto:rjohn088@ucr.edu">rjohn088@ucr.edu</a>>, Vladimir López <<a href="mailto:vlope166@ucr.edu">vlope166@ucr.edu</a>>, Rim Hammoud <<a href="mailto:rhamm009@ucr.edu">rhamm009@ucr.edu</a>>, Seth Berman <<a href="mailto:sberm026@ucr.edu">sberm026@ucr.edu</a>>, Qiang Kang <<a href="mailto:qkang003@ucr.edu">qkang003@ucr.edu</a>>, Ethan Nowaski <<a href="mailto:enowa001@ucr.edu">enowa001@ucr.edu</a>>, Taylor Fisher <<a href="mailto:gfish007@ucr.edu">gfish007@ucr.edu</a>>, Vas Shik <<a href="mailto:vshik001@ucr.edu">vshik001@ucr.edu</a>>, Kimberly Alexander <<a href="mailto:kalex026@ucr.edu">kalex026@ucr.edu</a>>, Emerald Win <<a href="mailto:ewin002@ucr.edu">ewin002@ucr.edu</a>>, Khoi Vo <<a href="mailto:kvo020@ucr.edu">kvo020@ucr.edu</a>><br></div><br><br><div dir="ltr"><div class="gmail_quote"><div dir="ltr" class="gmail_attr"><br></div><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div dir="ltr">Dear All,</div><div dir="ltr"><br></div><div>Please join us for the Mathematics Colloquium/ICQMB Lecture this Wednesday.</div><div> </div><div>Prof. Eric Cytrynbaum</div><div>Department of Mathematics</div><div>University of British Columbia</div><div>Canada</div><div><br></div><div dir="ltr"><div dir="ltr" class="gmail_signature"><div dir="ltr"><div><div><b>Time: </b>Wed. Nov. 06, 2pm-3pm.</div><div><b>Location: </b>Skye Hall 361</div></div><div><br></div><div><b style="font-family:Aptos,sans-serif">Title</b><span style="font-family:Aptos,sans-serif">: Mathematical models of spatiotemporal organization in multicellular organisms</span></div><div><br></div><div>The Abstract of the talk is provided below.</div><div><br></div><div>We look forward to seeing you on Wednesday. </div><div><br></div><div>Best regards,</div><div><br></div><div>Jia Gou and Mark Alber</div><div>____________________________________________________________________________________________________________________</div><div><p class="MsoNormal" style="text-align:center;margin:0in;font-size:12pt;font-family:Aptos,sans-serif"><b style="font-family:Aptos,sans-serif"><span style="font-size:14pt;font-family:Aptos,sans-serif;color:rgb(0,112,192)"><br></span></b></p><p class="MsoNormal" style="text-align:left;margin:0in;font-family:Aptos,sans-serif"><b style="font-family:Aptos,sans-serif"><span style="font-family:Aptos,sans-serif;color:rgb(0,112,192)">Mathematics Colloquium and ICQMB Lecture</span></b></p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif"> </p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif">Eric Cytrynbaum</p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif">Department of Mathematics</p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif">University of British Columbia</p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif">Canada</p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif"> </p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif"><b style="font-family:Aptos,sans-serif">Time: </b>Wed. Nov. 06, 2pm-3pm.</p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif"><b style="font-family:Aptos,sans-serif">Location: </b>Skye Hall 361</p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif"> </p>
<p class="MsoNormal" style="margin:0in;font-family:Aptos,sans-serif"><b style="font-family:Aptos,sans-serif">Title</b>: Mathematical models of spatiotemporal
organization in multicellular organisms<br>
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<b style="font-family:Aptos,sans-serif">Abstract</b>: In this talk, I’ll discuss two recent lines of research in my
group, related by the common element of being a multiscale problem of spatial
organization.<br>
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(1) For over a century, the development and replacement of reptile teeth has
been of interest in comparative anatomy and evolutionary biology due to the
prevalence of teeth in the fossil record and, more recently, for understanding
spatiotemporal patterning in developmental biology as well as the fundamentals
of tooth replacement for a clinical context. In collaboration with the Richman
Lab (UBC Dentistry), we are using the Leopard Gecko as a model organism to
understand the mechanisms underlying the regular and long-lasting
spatiotemporal patterns of tooth replacement seen in many polyphyodonts. I will
describe the data and our implementation and analysis of several mechanisms
that have been proposed in the past to explain the observations. Finding
shortcomings in these models, we propose a new model, the Phase Inhibition
Model, a coupled phase oscillator model, which does better at explaining the
data.<br>
<br>
(2) Many externally bilaterally symmetric animals, including both vertebrates
and invertebrates, have an internal left-right asymmetry that is established
during embryo development. This asymmetry can be critical for proper organ
function (e.g. the mammalian heart). In C. elegans, left-right asymmetry
(chirality) arises during cell division at the four-cell stage and eventually
manifests in a consistent handedness in the twisting of intestine and gonad in
the adult. In collaboration with the Sugioka Lab (UBC Zoology), we are
developing models to explain the onset of chirality. Chirality appears
intracellularly during cell division in the form of chiral flow of the actomyosin
cortex. We hypothesize that this flow induces friction forces between neighboring
cells mediated by adhesions. The model takes the form of force balance
differential equations and does well in comparison with quantitative data
extracted from live-cell and in vitro imaging.<br>
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