[IIGBCORES_All] Special Seminar 03/18/2025 from Prof. Lionel Navarro: Extracellular small RNAs in host-bacteria interactions

[IIGBadmin IIGBadmin]

Special In-Person Seminar: at Noon March 18 (tomorrow), Genomics Auditorium

[image: Screenshot 2025-03-17 at 9.09.05 AM.png]

*Prof. Lionel Navarro from Institut de Biologie de l’École normale
supérieure (IBENS), France*

*Extracellular small RNAs in host-bacteria interactions*


Extracellular plant small RNAs (sRNAs) act as triggers of RNAi in
interacting fungal and oomycetal pathogens. However, whether these
extracellular RNA species direct gene silencing in plant-associated
bacteria, which are thought to lack a canonical eukaryotic-like RNAi
machinery, remains unknown. Here, I will present recent findings from the
lab demonstrating the occurrence of a cross-kingdom RNAi phenomenon
implicating the trafficking of sRNAs from plant cells towards bacterial
cells. In particular, I will report on the vesicular and non-vesicular
extracellular sRNAs that are causal for this gene regulatory process.
Finally, I will touch upon approaches that are currently developed to
translate these discoveries towards novel solutions to control bacterial
infections in plants and mammals.
-- 

Respectfully,

IIGB Office



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| Useful Links <https://iigb.ucr.edu/department-resources>*
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