<div dir="ltr"><div dir="ltr"><div class="gmail_quote"><div dir="ltr"><div class="gmail_quote"><br><div dir="ltr"><div dir="ltr"><div><div style="text-align:center"><img src="cid:ii_mfo8yc771" alt="iigb logo 2.PNG" width="365" height="56" style="margin-right:0px"></div><div style="text-align:center"><font face="georgia, serif" size="6"><b>Matt Traxler</b></font></div><div style="text-align:center"><img src="cid:ii_mlr5f5q70" alt="image.png" width="204" height="276"><br></div><div style="text-align:center"><font face="georgia, serif"></font></div><div style="text-align:center"><font face="georgia, serif" size="4" color="#073763"><b>Leveraging microbial interactions for discovery of global regulators and small molecules</b></font></div><p style="text-align:center;direction:ltr;line-height:1.2;margin-top:4.2pt;margin-right:48.8pt;margin-bottom:0px"><span style="text-align:left"><font face="georgia, serif"><br></font></span></p><p style="text-align:center;direction:ltr;line-height:1.2;margin-top:0.5pt;margin-right:48.8pt;margin-bottom:0px"><font face="georgia, serif"><span style="font-size:12pt;color:black"><b> Date:</b> Friday, February 27</span></font></p><p style="text-align:center;direction:ltr;line-height:1.2;margin-top:0.5pt;margin-right:48.8pt;margin-bottom:0px"><span style="font-size:12pt;color:black"><font face="georgia, serif"><b> Time:</b> 12:00 pm-1:00pm</font></span></p><p style="text-align:center;direction:ltr;line-height:1.2;margin-top:0.5pt;margin-right:48.8pt;margin-bottom:0px"><font face="georgia, serif"><b style="color:black;font-size:12pt"> Location: </b><span style="color:black;font-size:12pt">Genomics Auditorium 1102</span></font></p><p style="text-align:center;direction:ltr;line-height:1.2;margin-top:0.5pt;margin-right:48.8pt;margin-bottom:0px"><span style="font-size:12pt;color:black"><font face="georgia, serif"><br></font></span></p><p style="direction:ltr;text-align:center;line-height:1.2;margin-top:0px;margin-right:48.8pt;margin-bottom:0px"><span style="color:black"><b><font face="georgia, serif" size="4">Abstract:</font></b></span></p><font face="georgia, serif" size="4">Bacteria are incredible biochemists, capable of producing molecules with functions that range from interspecies communication to all-out chemical warfare. One group of bacteria, the actinomycetes, has been the deepest source of these natural products, and they have the genetic capacity to give us many more. The goals of our work are to understand the molecular and ecological drivers of specialized metabolism in the context of microbial interactions. In this talk, I will describe our recent work examining a regulatory system that controls specialized metabolism in the model actinomycete, Streptomyces coelicolor. This regulatory system is an example of an unusual mode of bacterial regulation that utilizes a G protein, much like eukaryotic signaling systems. I will also present our findings about molecules made during microbial interactions, and discuss how microbial interactions can be a source for novel molecule discovery.</font></div></div></div></div></div></div><div dir="ltr" class="gmail_signature" data-smartmail="gmail_signature"><div dir="ltr"></div></div></div>
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