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<b><span style="font-size:20.0pt;font-family:inherit;color:red;border:none windowtext 1.0pt;padding:0in">IMPORTANT!! IMPORTANT! IMPORTANT!!</span></b><span style="font-size:20.0pt;color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:20.0pt;font-family:inherit;color:red;border:none windowtext 1.0pt;padding:0in">Genomics Core facilities will be closed for the holidays from Friday Dec 22nd until Tuesday Jan 2nd.</span></b><span style="font-size:20.0pt;color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in"> </span></b><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#1F497D;border:none windowtext 1.0pt;padding:0in">T</span></b><b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">he following services within
the Genomics Core will be unavailable during this break:<o:p></o:p></span></b></p>
<p class="xmsonormal" style="margin:0in;background:white"><span style="color:#242424"><o:p> </o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">1. Sanger DNA sequencing </span></b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">- <b><u>Please
note that samples received before 3PM Wednesday Dec 20th will be posted by the 22<sup>nd</sup>.</u></b> Samples received after this time cannot be guaranteed to be posted via Google link before the break begins. Any samples not posted before the break will
be processed upon re-opening on the 2nd.</span><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">2. Illumina sequencing services –</span></b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in"> these
services will be processed on a first come, first serve basis up until we leave for break on the 22nd.<o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white"><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">You may keep submitting samples for QC during the closure, they will be processed after the break.
</span><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">3.</span></b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in"> <b>Bioanalyzer, Tapestation, and
Fragment Analyzer services</b>- these services will be processed on a first come, first serve basis up until we leave for break on the 22nd.<o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white"><b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">4. Illumina Library prep</span><span style="color:#242424"><o:p></o:p></span></b></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in"> </span></b><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">Points to keep in mind:</span></b><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">1. Please plan your experiments in advance.
</span></b><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">2. Access</span></b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">. Those with key fobs
to the instrumentation labs will have access to instruments (qPCR, Typhoon, Nanodrop, Qubit, plate readers, Covaris) during this time. As always, reserve or log your time online prior to instrument use.</span><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">3. Covaris.</span></b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in"> Our new ME220 is here,
so please get training before the break if you plan to use it. <u>Remember to obtain your tubes before the break.</u></span><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">3. Please be sure your key fob is current.</span></b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in"> If
you have not used it in some time, please check it. If in doubt, ask Ben or Amanda (room 1206, 1st floor of Genomics Building), so that you are not locked out during the break.</span><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">4. Security</span></b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">. We cannot emphasize
strongly enough that our security system has two key components: Security zones with individual key fobs and YOU. Security during the break is everyone's responsibility.<o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white"><u><span style="font-size:14.0pt;font-family:inherit;color:red;border:none windowtext 1.0pt;padding:0in">Please never prop open external or internal doors or leave them ajar. NEVER admit anyone who does
not have a fob. NEVER admit anyone who you do not recognize!</span></u><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">
<o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white"><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">Think of the impact on your research and that of your colleagues if we were vandalized or there
was a major theft.<o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white"><b><span style="font-size:14.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in">5. Please send an email directly to Wei Zhang (<a href="mailto:wezhang@ucr.edu">wezhang@ucr.edu</a>),
Clay Clark (<a href="mailto:clayc@ucr.edu">clayc@ucr.edu</a>) and/or Holly Clark (<a href="mailto:holly.clark@ucr.edu">holly.clark@ucr.edu</a>) if you notice anything – freezer alarms, propped doors, malfunctioning equipment, etc.
</span><span style="color:#242424"><o:p></o:p></span></b></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<span style="font-size:18.0pt;font-family:inherit;color:#242424;border:none windowtext 1.0pt;padding:0in"> </span><span style="color:#242424"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:18.0pt;font-family:inherit;color:#0070C0;border:none windowtext 1.0pt;padding:0in">Thank you for all your support and have the very best holiday ever!</span></b><span style="color:#0070C0"><o:p></o:p></span></p>
<p class="xmsonormal" style="margin:0in;background:white;font-variant-ligatures: normal;font-variant-caps: normal;orphans: 2;text-align:start;widows: 2;-webkit-text-stroke-width: 0px;text-decoration-thickness: initial;text-decoration-style: initial;text-decoration-color: initial;word-spacing:0px">
<b><span style="font-size:18.0pt;font-family:inherit;color:#0070C0;border:none windowtext 1.0pt;padding:0in">Your Genomics Core</span></b><span style="color:#0070C0"><o:p></o:p></span></p>
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