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<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif">With warm greetings for a powerful 2023, I would like to provide you with a summary of IIGB’s most notable activities in 2022, and a brief summary
of the current plans for the 2023. <o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif">In 2022, with input from some of you, IIGB managed to attract and hire competent, engaged and knowledgeable colleagues who are now in charge of
the metabolomics, proteomics and genomic cores. I strongly believe that with the new teams we are in a strong position to further our research activities and teaching missions.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif">In 2022 under the leadership of Xuemei Chan, and in collaboration with
</span><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Seán O'Leary and Weifeng Gu, the sequencing facility obtained several much-needed instrumentations. In addition, the Lottery funds from CNAS, funds from IIGB and funds form
the genomic core enabled the purchase of additional equipment listed below. <o:p>
</o:p></span></p>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">NextSeq 2000 sequencing
<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Short reads (NGS) sequencer<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Lottery funding
<o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">TapeStation 4150<o:p></o:p></span></p>
</td>
<td width="207" nowrap="" valign="bottom" style="width:155.0pt;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">DNA/RNA quality control<o:p></o:p></span></p>
</td>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Seán O'Leary, NIH<o:p></o:p></span></p>
</td>
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<td width="241" nowrap="" valign="bottom" style="width:181.0pt;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">SpectraMax iD5 Microplate
<o:p></o:p></span></p>
</td>
<td width="207" nowrap="" valign="bottom" style="width:155.0pt;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Microplate Reader<o:p></o:p></span></p>
</td>
<td width="168" nowrap="" valign="bottom" style="width:1.75in;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Xuemei Chan, NIH<o:p></o:p></span></p>
</td>
</tr>
<tr style="height:16.0pt">
<td width="241" nowrap="" valign="bottom" style="width:181.0pt;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Amersham Typhoon RGB<o:p></o:p></span></p>
</td>
<td width="207" nowrap="" valign="bottom" style="width:155.0pt;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Gel Image analysis<o:p></o:p></span></p>
</td>
<td width="168" nowrap="" valign="bottom" style="width:1.75in;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Weifeng Gu, NIH
<o:p></o:p></span></p>
</td>
</tr>
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<td width="241" nowrap="" valign="bottom" style="width:181.0pt;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">ME220 ultrasonicator
<o:p></o:p></span></p>
</td>
<td width="207" nowrap="" valign="bottom" style="width:155.0pt;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">DNA shearing/Cell lysis<o:p></o:p></span></p>
</td>
<td width="168" nowrap="" valign="bottom" style="width:1.75in;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">IIGB funds<o:p></o:p></span></p>
</td>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Thermal Cycler<o:p></o:p></span></p>
</td>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">PCR<o:p></o:p></span></p>
</td>
<td width="168" nowrap="" valign="bottom" style="width:1.75in;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Genomics Core<o:p></o:p></span></p>
</td>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">MinION<o:p></o:p></span></p>
</td>
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<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Long reads sequencer<o:p></o:p></span></p>
</td>
<td width="168" nowrap="" valign="bottom" style="width:1.75in;padding:0in 5.4pt 0in 5.4pt;height:16.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Genomics Core<o:p></o:p></span></p>
</td>
</tr>
<tr style="height:2.0pt">
<td width="241" nowrap="" valign="bottom" style="width:181.0pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;height:2.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Flongle<o:p></o:p></span></p>
</td>
<td width="207" nowrap="" valign="bottom" style="width:155.0pt;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;height:2.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Long reads adapter<o:p></o:p></span></p>
</td>
<td width="168" nowrap="" valign="bottom" style="width:1.75in;border:none;border-bottom:solid windowtext 1.0pt;padding:0in 5.4pt 0in 5.4pt;height:2.0pt">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Genomics Core<o:p></o:p></span></p>
</td>
</tr>
</tbody>
</table>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">Hopefully, these additions will empower UCR research activities.
<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black"><o:p> </o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif;color:black">In 2023, our current plans are as follows:<o:p></o:p></span></p>
<ol style="margin-top:0in" start="1" type="1">
<li class="MsoListParagraphCxSpFirst" style="margin-left:0in;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1">
<span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif">To replace the auditorium’s current AV with an advanced system to meet the in person and the online seminar and teaching requirements. CNAS has generously agreed to cover the
substantial costs associated with the replacement, currently scheduled for summer 2023.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="margin-left:0in;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1">
<span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif">We will be replacing the semi functional autoclaves, one or two per year depending on the IIGB budgetary constraints, starting this year.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="margin-left:0in;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1">
<span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif">I together with the Dr. Amancio De Souza and Quanqing Zhang will be applying for an NSF/MRI grant for the purchase of Ascend (<b>dual-purpose Mass Spec for Metabolomics and
Proteomics of a single cell). </b>I like to thank my colleagues who have provided a support letter for this application.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="margin-left:0in;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1">
<span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif">We were successful in attracting one of the top biochemist/metabolomics researchers, Adam Jozwiak currently at the Weizmann institute, to UCR. Adam will be joining us in July
2023, and I am certain that his knowledge and analytical mind will be an asset for our campus.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="margin-left:0in;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1">
<span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif">In 2023 we will be recruiting a new admin to replace
<span style="color:black">Frank Figueroa</span> who has accepted a position in finance in CNAS.<o:p></o:p></span></li><li class="MsoListParagraphCxSpMiddle" style="margin-left:0in;mso-add-space:auto;text-align:justify;mso-list:l0 level1 lfo1">
<span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif">There are other irons in fire, and I will inform you with details, as soon as I have a better framework going forward.
<o:p></o:p></span></li></ol>
<p class="MsoListParagraphCxSpMiddle" style="text-align:justify"><span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif"><o:p> </o:p></span></p>
<p class="MsoListParagraphCxSpLast" style="margin-left:4.5pt;mso-add-space:auto;text-align:justify">
<span style="font-size:12.0pt;line-height:106%;font-family:"Times New Roman",serif">I wish you all much power in 2023 and beyond.<o:p></o:p></span></p>
<p class="MsoNormal" style="text-align:justify"><span style="font-size:12.0pt;font-family:"Times New Roman",serif"> Katie<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Katayoon (Katie) Dehesh<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Director, Institute for Integrative Genome Biology, Distinguished Professor
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Ernst and Helen Leibacher Endowed Chair in Botany and Plant Sciences<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">University of California, Riverside, CA 92521<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Phone: (951) 827-6370; Fax: (951) 827-5155<o:p></o:p></span></p>
<p class="MsoNormal"><o:p> </o:p></p>
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