<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv="Content-Type" content="text/html; charset=utf-8">
<meta name="Generator" content="Microsoft Word 15 (filtered medium)">
<style><!--
/* Font Definitions */
@font-face
{font-family:Helvetica;
panose-1:2 11 6 4 2 2 2 2 2 4;}
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:Georgia;
panose-1:2 4 5 2 5 4 5 2 3 3;}
@font-face
{font-family:goergia;
panose-1:0 0 0 0 0 0 0 0 0 0;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0in;
font-size:11.0pt;
font-family:"Calibri",sans-serif;}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:blue;
text-decoration:underline;}
p.MsoListParagraph, li.MsoListParagraph, div.MsoListParagraph
{mso-style-priority:34;
mso-margin-top-alt:auto;
margin-right:0in;
mso-margin-bottom-alt:auto;
margin-left:0in;
font-size:11.0pt;
font-family:"Calibri",sans-serif;}
span.apple-converted-space
{mso-style-name:apple-converted-space;}
span.EmailStyle20
{mso-style-type:personal-reply;
font-family:"goergia",serif;
color:windowtext;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:10.0pt;}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
/* List Definitions */
@list l0
{mso-list-id:352846134;
mso-list-template-ids:1489908436;}
@list l1
{mso-list-id:383604791;
mso-list-template-ids:580414450;}
@list l1:level1
{mso-level-start-at:2;
mso-level-tab-stop:.5in;
mso-level-number-position:left;
text-indent:-.25in;}
ol
{margin-bottom:0in;}
ul
{margin-bottom:0in;}
--></style><!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body lang="EN-US" link="blue" vlink="purple" style="word-wrap:break-word">
<div class="WordSection1">
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif">Greetings Karine et al<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif">I certainly am in support of the genomic core and the reconstitution of its function as a powerful, and not semi functional core. I agree with Karine’s analyses.
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif">I am hoping that as a collective we can convince the administration to support the cores as a critical service for all.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif">Please help us as a community to convey a strong message to the campus leadership. I will get back to you after some deliberation, finding ways to do this constructively and effectively.<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif">Be powerful<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif">Katie<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif"><o:p> </o:p></span></p>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Katayoon (Katie) Dehesh<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Director, Institute for Integrative Genome Biology, Distinguished Professor
<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Ernst and Helen Leibacher Endowed Chair in Botany and Plant Sciences<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">University of California, Riverside, CA 92521<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Phone: (951) 827-6370; Fax: (951) 827-5155<o:p></o:p></span></p>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D"><o:p> </o:p></span></p>
</div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"goergia",serif"><o:p> </o:p></span></p>
<div>
<div style="border:none;border-top:solid #E1E1E1 1.0pt;padding:3.0pt 0in 0in 0in">
<p class="MsoNormal"><b>From:</b> Karine Le Roch <karinel@ucr.edu> <br>
<b>Sent:</b> Monday, August 29, 2022 10:16 AM<br>
<b>To:</b> Katayoon Dehesh <katayoon.dehesh@ucr.edu><br>
<b>Cc:</b> IIGB_All@lists.ucr.edu; bpsfaculty@lists.ucr.edu; IIGBadmin <iigbadmin@ucr.edu><br>
<b>Subject:</b> Re: [IIGB_All] Your input is crucial<br>
<b>Importance:</b> High<o:p></o:p></p>
</div>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif">Dear Katie and IIGB faculty, </span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify;line-height:11.55pt">
<span style="font-family:"Arial",sans-serif">While I think both the Nanopore GridION and the Orbitrap ASCEND would be great additions to the cores, the question posed to the faculty in the survey/vote did not contain all the information needed to make an informed
decision. </span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify;line-height:11.55pt">
<span style="font-family:"Arial",sans-serif">Hence, before the faculty vote on how best to use the lottery funds, I would like to let the IIGB faculty know what we accomplished this past year while Xuemei was the IIGB interim director while Katie was on sabbatical. </span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify;line-height:11.55pt">
<span style="font-family:"Arial",sans-serif">As many of you know, our Genomics core was outdated and nonfunctional. Xuemei, together with Julia, the staff at the core and myself, generated a list of instruments that were critical to reviving the core.
</span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify;line-height:11.55pt">
<i><span style="font-family:"Arial",sans-serif">The NextSeq2000, together with other smaller instruments, were listed as essential for the day-to-day activity of the core and are the bread and butter of the Genomics core. </span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif">Xuemei, together with Weifeng Gu and Sean O’Leary, managed to secure new NIH funding to bring to the core 1) a new <span style="color:#222222">Typhoon RGB Imager, 2) a new Luminometer (Plate reader); and 3) a Tapestation
(similar as </span>Qsep 100<span style="color:#222222">). </span></span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif;color:#222222">Please join me in thanking </span></i><i><span style="font-family:"Arial",sans-serif">Xuemei, Weifeng Gu and Sean O’Leary<span style="color:#222222"> for their hard work!</span></span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif;color:#222222">In addition, Xuemei, Julia and I lobbied the upper administration and secured additional funds ($530K, aka lottery funds) for the Genomics Core, including funds for the NextSeq2000.
</span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif;color:#222222">These funds will modernize the Genomics Core and make it truly functional once again.</span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif;color:#222222">This is critical for the success of many faculty on campus as well as our PhD students (lottery funds can only be spent on items that benefit the students)</span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif;color:#222222">With the lottery funds we can also purchase small instruments essential for sample preparation (Bioruptor) as well as the nanopore for long read sequencing.
</span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<b><span style="font-family:"Arial",sans-serif;color:#222222">We have a critical decision to make now:</span></b><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif;color:#222222">If the IIGB faculty decide to get the </span><span style="font-family:"Arial",sans-serif">Orbitrap ASCEND (over 1 million dollars) with the funds initially targeted for the Genomics Core, there will
be no money left for any small instruments nor any new sequencing platforms. </span>
<o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif">Please keep in mind that we cannot get small instruments through instrument grants.
</span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif">In short, by diverting the lottery funds to the new mass spectrometer, the Genomics core will be nonfunctional and would eventually disappear. </span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif">Furthermore, after several years without a fulltime Academic Coordinator for the Genomics Core, we finally recruited Dr. Wei Zhang, Ph.D<b>. </b>
</span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<span style="font-family:"Arial",sans-serif"> <i>Julia Bailey-Serres, Sydney Glassman, Quinn McFrederick and I, were part of the search committee, and we were thrilled to recruit Wei to UCR this Spring.
</i></span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif">If you have not met Wei yet, please take some time to do so now. She is fantastic!
</span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif">Wei and I already submitted a new NIH instrument Grant for a NOVAseq platform.</span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif">With proper instrumentation in the Genomics Core, Wei will be able to enable all of our research.</span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;margin-left:.5in;text-align:justify">
<i><span style="font-family:"Arial",sans-serif"> I am sure she will be happy to help any of us with additional instrumentation grants. </span></i><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif">We worked hard this past year to convince the upper admin of the importance of reviving the Genomics Core. If we do not take this opportunity now, it will not come again and I fear that the Genomics Core will disappear
altogether. In contrast, a new mass spectrometer can be funded through instrumentation grants as noted above.</span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif">Thank you all for your support,</span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif">Best,</span><o:p></o:p></p>
<p class="MsoNormal" style="mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;text-align:justify">
<span style="font-family:"Arial",sans-serif">Karine</span><o:p></o:p></p>
<div>
<p class="MsoNormal"><br>
<br>
<o:p></o:p></p>
<blockquote style="margin-top:5.0pt;margin-bottom:5.0pt">
<div>
<p class="MsoNormal">On Aug 26, 2022, at 11:55 AM, Katayoon Dehesh <<a href="mailto:katayoon.dehesh@ucr.edu">katayoon.dehesh@ucr.edu</a>> wrote:<o:p></o:p></p>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
<div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif">Dear Colleagues,</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif">The Dean informed me yesterday that the total lottery funds awarded to IIGB is $530K. This money can be spent for the purchase of any instrumentations with greater impacts on teaching
and research activities, albeit with a more focused view on the teaching outcome.</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif">There are two groups of instruments that fulfill the required criteria for the funds:</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<p class="MsoListParagraph" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:0in;margin-left:.75in;text-indent:-.25in;mso-line-height-alt:11.55pt;mso-list:l0 level1 lfo1">
<![if !supportLists]><span style="mso-list:Ignore">1.<span style="font:7.0pt "Times New Roman"">
</span></span><![endif]><span style="font-size:12.0pt;font-family:"Georgia",serif"> 10X Chromium: an instrument for single-cell genomics, bundled with<span class="apple-converted-space"> </span>GridION, a high-throughput long-read sequencer.</span><o:p></o:p></p>
<div style="margin-left:.75in">
<p class="MsoNormal" style="mso-line-height-alt:11.55pt"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<p class="MsoListParagraph" style="mso-margin-top-alt:0in;margin-right:0in;margin-bottom:0in;margin-left:.75in;text-indent:-.25in;mso-list:l1 level1 lfo2">
<![if !supportLists]><span style="mso-list:Ignore">2.<span style="font:7.0pt "Times New Roman"">
</span></span><![endif]><span style="font-size:12.0pt;font-family:"Georgia",serif">Orbitrap ASCEND mass spectrometer for high resolution proteomics and metabolomics. For this instrument we will need an extra 100K, however the Dean added that we will go to
the provost to secure the amount.</span><o:p></o:p></p>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif">Rather than making a unilateral decision, I am reaching out to ask for your input. It is important that we purchase the instrument with highest impact for most of our community.
To better assess your needs, I am sending the link below where you can state the choice of your preferred instrument. </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"><a href="https://docs.google.com/spreadsheets/d/1dR_moNhfllQmImap9_ik_CDHWDhE7cYzB56kLVKqB_4/edit?usp=sharing"><span style="color:#0563C1">https://docs.google.com/spreadsheets/d/1dR_moNhfllQmImap9_ik_CDHWDhE7cYzB56kLVKqB_4/edit?usp=sharing</span></a></span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif">Please provide your responses not later than the next Thursday September 1<sup>st</sup>. I will let you know outcome.</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif">Be powerful and thanks in advance for your input.</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif">Katie</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Katayoon (Katie) Dehesh</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Director, Institute for Integrative Genome Biology, Distinguished Professor</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Ernst and Helen Leibacher Endowed Chair in Botany and Plant Sciences</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">University of California, Riverside, CA 92521</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D">Phone: (951) 827-6370; Fax: (951) 827-5155</span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><span style="font-size:12.0pt;font-family:"Georgia",serif;color:#1F497D"> </span><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"> <o:p></o:p></p>
</div>
<p class="MsoNormal"><span style="font-size:9.0pt;font-family:"Helvetica",sans-serif">_______________________________________________<br>
IIGB_All mailing list<br>
</span><a href="mailto:IIGB_All@lists.ucr.edu"><span style="font-size:9.0pt;font-family:"Helvetica",sans-serif;color:#0563C1">IIGB_All@lists.ucr.edu</span></a><span style="font-size:9.0pt;font-family:"Helvetica",sans-serif"><br>
</span><a href="https://lists.ucr.edu/mailman/listinfo/iigb_all"><span style="font-size:9.0pt;font-family:"Helvetica",sans-serif;color:#0563C1">https://lists.ucr.edu/mailman/listinfo/iigb_all</span></a><o:p></o:p></p>
</div>
</blockquote>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
<div>
<div>
<p class="MsoNormal">K. Le Roch, PhD<br>
Professor of Molecular, Cell and Systems Biology<br>
Director Center for Infectious Disease and Vector Research<br>
Institute for Integrative Genome Biology<br>
Department of Molecular, Cell and Systems Biology (MCSB)<br>
University of California Riverside<br>
900 University Avenue<br>
Multidisciplinary Research Building (MRB) Room 3139<br>
Riverside, CA 92521, USA<br>
Phone office: (1) 951 827 54 22<br>
Phone Lab: (1) 951 827 5934<br>
Web Site: <a href="http://www.lerochlab.ucr.edu/">http://www.lerochlab.ucr.edu/</a><o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
</div>
</body>
</html>