<html><head><meta http-equiv="Content-Type" content="text/html; charset=us-ascii"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class="">Dear Colleagues,<div class=""><br class=""></div><div class="">Prof. Dae-Jin Yun from Konkuk University (Korea) will visit UCR and give a special seminar on plant cold tolerance at 10 AM this Wednesday. The following is the seminar information. Please let me know if you wish to meet with Prof. Yun after his seminar. </div><div class=""><br class=""></div><div class="">Title: <b class="">Epigenetic regulation of cold tolerance in plants</b></div><div class="">Speaker: Prof. <b class="">Dae-Jin Yun</b></div><div class="">Time: <b class="">10 AM, Jan 12 (Wednesday)</b></div><div class="">Synopsis:</div><div class="">
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<!--StartFragment--><p class="MsoNormal" style="margin-bottom:0in;text-indent:40.0pt;line-height:
115%;mso-layout-grid-align:none;word-break:normal"><span style="font-size:11.0pt;
line-height:115%;font-family:"Arial",sans-serif;color:#212121;background:white" class="">Switching
from repressed to active status in chromatin regulation is part of the critical
responses that plants deploy to survive in an ever-changing environment. We
found that HOS15, a WD40-repeat protein, is a substrate receptor of the
CULLIN4-based CLR4 ubiquitin E3 ligase complex, which epigenetically regulates
cold tolerance by degrading HISTONE DEACETYLASE2C (HD2C) to switch from
repressive to permissive chromatin structure in response to cold stress. </span><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;
mso-fareast-font-family:TT96o00;mso-font-kerning:0pt" class="">To identify the protein
complexes that function in conjunction with HOS15, we performed FLAG-tag affinity
purification using transgenic <i class="">Arabidopsis</i> plants expressing HOS15-FLAG and
isolated many HOS15-interacting proteins. Among them, we analyzed the function
of </span><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;
color:#212121;background:white" class="">POWERDRESS (PWR)</span><span style="mso-bidi-font-size:
10.0pt;line-height:115%;font-family:TT96o00;mso-hansi-font-family:"Malgun Gothic";
mso-hansi-theme-font:minor-latin;mso-font-kerning:0pt" class=""> </span><span style="font-size:11.0pt;line-height:115%;font-family:"Arial",sans-serif;
color:#212121;background:white" class="">in detail. PWR loss-of-function plants (<i class="">pwr</i>)
showed lower expression of cold-regulated (<i class="">COR</i>) genes and sensitivity to
freezing. PWR interacts with HD2C through HOS15, and cold-induced HD2C
degradation by HOS15 is diminished in the <i class="">pwr</i> mutant. The
association of HOS15 and HD2C to promoters of cold-responsive <i class="">COR</i> genes
was dependent on PWR. Consistent with these observations, the high acetylation
levels of histone H3 by cold-induced and HOS15-mediated HD2C degradation were
significantly reduced in <i class="">pwr</i> under cold stress. PWR also
interacts with C-repeat element-binding factor transcription factors to
modulate their cold-induced binding to the promoter of <i class="">COR</i> genes.
Collectively, our data signify that the PWR-HOS15-HD2C histone-modifying
complex regulates the expression of <i class="">COR</i> genes and the freezing
tolerance of plants.</span></p><div class=""><br class=""></div><div class="">Zoom link:</div><div class=""><div class=""><br class=""></div><div class="">Topic: Special Seminar by Prof. Dae-Jin Yan</div><div class="">Time: Jan 12, 2022 10:00 AM Pacific Time (US and Canada)</div><div class=""><br class=""></div><div class=""><b class="">Join Zoom Meeting</b></div><div class=""><a href="https://ucr.zoom.us/j/95753633903?pwd=dFpOQUVsY0Vid0oyREUzOTZpWFVlZz09" class="">https://ucr.zoom.us/j/95753633903?pwd=dFpOQUVsY0Vid0oyREUzOTZpWFVlZz09</a></div><div class=""><br class=""></div><div class="">Meeting ID: 957 5363 3903</div><div class="">Passcode: 041180</div><div class="">One tap mobile</div><div class="">+16699006833,,95753633903# US (San Jose)</div><div class="">+13462487799,,95753633903# US (Houston)</div><div class=""><br class=""></div><div class="">Dial by your location</div><div class=""> +1 669 900 6833 US (San Jose)</div><div class=""> +1 346 248 7799 US (Houston)</div><div class=""> +1 253 215 8782 US (Tacoma)</div><div class=""> +1 312 626 6799 US (Chicago)</div><div class=""> +1 646 876 9923 US (New York)</div><div class=""> +1 301 715 8592 US (Washington DC)</div><div class="">Meeting ID: 957 5363 3903</div><div class="">Find your local number: <a href="https://ucr.zoom.us/u/acyzdV4wVO" class="">https://ucr.zoom.us/u/acyzdV4wVO</a></div><div class=""><br class=""></div><div class="">Join by SIP</div><div class=""><a href="mailto:95753633903@zoomcrc.com" class="">95753633903@zoomcrc.com</a></div><div class=""><br class=""></div><div class="">Join by H.323</div><div class="">162.255.37.11 (US West)</div><div class="">162.255.36.11 (US East)</div><div class="">115.114.131.7 (India Mumbai)</div><div class="">115.114.115.7 (India Hyderabad)</div><div class="">213.19.144.110 (Amsterdam Netherlands)</div><div class="">213.244.140.110 (Germany)</div><div class="">103.122.166.55 (Australia Sydney)</div><div class="">103.122.167.55 (Australia Melbourne)</div><div class="">149.137.40.110 (Singapore)</div><div class="">64.211.144.160 (Brazil)</div><div class="">149.137.68.253 (Mexico)</div><div class="">69.174.57.160 (Canada Toronto)</div><div class="">65.39.152.160 (Canada Vancouver)</div><div class="">207.226.132.110 (Japan Tokyo)</div><div class="">149.137.24.110 (Japan Osaka)</div><div class="">Meeting ID: 957 5363 3903</div><div class="">Passcode: 041180</div><div class=""><br class=""></div></div><div class="">Best,</div><div class=""><br class=""></div><div class="">Meng</div><div class=""><br class=""></div>
<!--EndFragment--></div><div class=""><div class="">
<div dir="auto" style="caret-color: rgb(0, 0, 0); color: rgb(0, 0, 0); letter-spacing: normal; text-align: start; text-indent: 0px; text-transform: none; white-space: normal; word-spacing: 0px; -webkit-text-stroke-width: 0px; text-decoration: none; word-wrap: break-word; -webkit-nbsp-mode: space; line-break: after-white-space;" class="">-- <br class="">Meng Chen<br class="">Department of Botany & Plant Sciences<br class="">University of California, Riverside <br class="">Website: <a href="http://www.plasticgenome.org/" class="">http://www.plasticgenome.org/</a></div>
</div>
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