<div dir="ltr"><font face="times new roman, serif">Hi all, </font><div><font face="times new roman, serif"><br></font></div><div><font face="times new roman, serif">Our session will start in about 2 hours at 2:00pm. Coffee and pizza will be served at the location!</font></div><div><font face="times new roman, serif"><br></font></div><div><font face="times new roman, serif">To attend on zoom:<br></font><div style="color:rgb(49,49,49);word-spacing:1px;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)"><a href="https://ucr.zoom.us/j/92738986667?pwd=RVpVdXJvS21jSnB6L3o1YWh5N08yUT09" target="_blank" style="color:rgb(66,133,244);background-color:rgba(0,0,0,0);border-color:rgb(66,133,244)"><font face="times new roman, serif">https://ucr.zoom.us/j/92738986667?pwd=RVpVdXJvS21jSnB6L3o1YWh5N08yUT09</font></a></div></div><div style="color:rgb(49,49,49);word-spacing:1px;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div style="color:rgb(49,49,49);word-spacing:1px;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)"><font face="times new roman, serif">Hope to see you there!</font></div><div style="color:rgb(49,49,49);word-spacing:1px;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div style="color:rgb(49,49,49);word-spacing:1px;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)"><font face="times new roman, serif">Best regards, </font></div><div style="color:rgb(49,49,49);word-spacing:1px;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)"><font face="times new roman, serif">Navaira Sherwani</font></div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Thu, Feb 22, 2024 at 1:43 PM Navaira Sherwani <<a href="mailto:navaira.sherwani@email.ucr.edu">navaira.sherwani@email.ucr.edu</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr"><div dir="ltr"><font face="times new roman, serif">Hi all, </font><div><font face="times new roman, serif"><br></font></div><div><font face="times new roman, serif">Just a reminder that we will be having our next SSB seminar tomorrow (Friday 02/23/2024) from 2:00pm to 3:00pm in SSC Multi-Purpose Room 3 (Ground Floor). Coffee and pizza will be served at 1:45pm!</font></div><div><font face="times new roman, serif"><br></font></div><div><font face="times new roman, serif">For those of you who cannot join in person the seminar is available to attend on zoom.<br><br></font><font face="times new roman, serif" style="color:rgb(49,49,49);word-spacing:1px"><b>Zoom Link:</b> </font><div style="color:rgb(49,49,49);word-spacing:1px;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)"><a href="https://ucr.zoom.us/j/92738986667?pwd=RVpVdXJvS21jSnB6L3o1YWh5N08yUT09" style="color:rgb(66,133,244);background-color:rgba(0,0,0,0);border-color:rgb(66,133,244)" target="_blank"><font face="times new roman, serif">https://ucr.zoom.us/j/92738986667?pwd=RVpVdXJvS21jSnB6L3o1YWh5N08yUT09</font></a></div></div><div><font face="times new roman, serif"><br></font></div><div><font face="times new roman, serif">I would like to request the faculty to please forward this to your respective departments. </font></div><div><font face="times new roman, serif"><br></font></div><div><font face="times new roman, serif">Hope to see you there!</font></div><div><font face="times new roman, serif"><br></font></div><div><font face="times new roman, serif">Best regards, </font></div><div><font face="times new roman, serif">Navaira Sherwani</font></div></div><br><div class="gmail_quote"><div dir="ltr" class="gmail_attr">On Thu, Feb 15, 2024 at 12:34 PM Navaira Sherwani <<a href="mailto:nsher012@ucr.edu" target="_blank">nsher012@ucr.edu</a>> wrote:<br></div><blockquote class="gmail_quote" style="margin:0px 0px 0px 0.8ex;border-left:1px solid rgb(204,204,204);padding-left:1ex"><div dir="ltr"><div><div style="background-color:rgba(0,0,0,0);border-color:rgb(255,255,255);color:rgb(255,255,255)"><span style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;float:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49);display:inline"><font face="times new roman, serif">Dear All,</font></span><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div dir="auto" style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif">We are happy to announce the next seminar in our fortnightly series of Biophysics Seminars coming up at the end of next week, during which Dr. Weitao Chen from the Department of Mathematics will be giving a talk featuring her work in Applied Mathematics. Details about the talk can be found below:</font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div dir="auto" style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><b style="background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)">Location</b>: Student Success Center - Multi-Purpose Room 3 (Ground Floor)</font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div dir="auto" style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><b style="background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)">Date + Time</b>: Friday, February 23rd, from 2:00 PM - 3:00 PM</font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div dir="auto" style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><b style="background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)">Speaker</b>: Dr. Weitao Chen</font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div style="font-style:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)" dir="auto"><b><font face="times new roman, serif">Title: </font></b><b style="background-color:rgba(0,0,0,0)"><div style="border-color:rgb(212,212,213);display:inline"><font face="times new roman, serif"><span style="font-weight:400;text-align:center;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49)">A Mechanochemical Coupled Model to Understand Budding Behavior in Aging Yeast</span> </font></div></b></div><div style="font-style:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(212,212,213);color:rgb(212,212,213)" dir="auto"><font face="times new roman, serif"><font style="color:rgb(49,49,49)"><b>Abstract: </b></font></font><span style="font-family:"times new roman",serif;background-color:rgba(0,0,0,0);color:rgb(49,49,49);text-align:justify">Cell polarization, in which a uniform distribution of substances becomes asymmetric due to internal or external stimuli, is a fundamental process underlying cell mobility and cell division. Budding yeast provides a good system to study how biochemical signals and mechanical properties coordinate with each other to achieve stable cell polarization and give rise to certain morphological change in a single cell. Recent experimental data suggests yeast budding develops into two trajectories with different bud shapes as mother cells become old. We first developed a 2D model to simulate biochemical signals on a shape-changing cell and investigated strategies for robust yeast mating. Then we extended and coupled this biochemical signaling model with a 3D subcellular element model to take into account cell mechanics, which was applied to investigate how the interaction between biochemical signals and mechanical properties affects the cell polarization and budding initiation. This 3D mechanochemical model was also applied to predict mechanisms underlying different bud shape formation due to cellular aging. </span></div><div dir="auto" style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif">For those who cannot attend in person, this talk is also available online.</font></div><div dir="auto" style="font-style:normal;font-variant-caps:normal;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><b>Zoom Link:</b> </font><div style="font-weight:400;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><a href="https://ucr.zoom.us/j/92738986667?pwd=RVpVdXJvS21jSnB6L3o1YWh5N08yUT09" style="background-color:rgba(0,0,0,0);border-color:rgb(66,133,244);color:rgb(66,133,244)" target="_blank"><font face="times new roman, serif">https://ucr.zoom.us/j/92738986667?pwd=RVpVdXJvS21jSnB6L3o1YWh5N08yUT09</font></a></div></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><br></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><span style="font-family:"times new roman",serif;background-color:rgba(0,0,0,0)">I would like to request the faculty to forward these to their department graduate students and postdocs.</span></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><span style="font-family:"times new roman",serif;background-color:rgba(0,0,0,0)"><br></span></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><span style="font-family:"times new roman",serif;background-color:rgba(0,0,0,0)">A note to Biophysics students, this seminar counts towards the BPHY 252 seminar series. </span><br></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif">Thank You!</font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif"><br></font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif">Best regards, </font></div><div style="font-style:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;text-align:start;text-indent:0px;text-transform:none;white-space:normal;word-spacing:1px;text-decoration:none;background-color:rgba(0,0,0,0);border-color:rgb(49,49,49);color:rgb(49,49,49)"><font face="times new roman, serif">Navaira Sherwani</font></div><br></div>
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