[Bphyfaculty] [Ssb_members] Colloquium ICDMB May 13 2026.pdf

[Navaira Sherwani via SSB_members]

Dear all,

I would like to encourage you to attend Mathematics Colloquium talk next
Wednesday, May 13th.
Dr. Mogilner is one of the leading mathematical biologists and applied
mathematicians.

Sincerely,

Mark Alber
_________________________________________________________________

This Colloquium talk is co-sponsored by the Department of Mathematics and
Interdisciplinary
Center for Data-driven Modeling in Biology.

Prof. Alex Mogilner
Courant Institute of Mathematical Sciences and the Department of Biology
New York University, NYC

May 13th, Wednesday, 2026
4:00 - 5:00 p.m.
Skye Hall 284

TITLE: Deciphering self-assembly of mitotic spindle

ABSTRACT: Mitotic spindle, a remarkable molecular machine, self-assembles
to segregate
chromosomes at the onset of cell division. Spindle assembles in phase, one
of the earliest
and least understood stages of mitosis. We used high-resolution 3D
measurements of movements
and deformations of chromosomes and spindle in prometaphase coupled with
computational modeling
to decipher force balances and speed and accuracy of integration of
chromosomes into the spindle.
I will describe how mathematical models are built from microscopy data and
demonstrate that
rapid stochastic interactions within the spindle leads to rapid, precise
and robust self-assembly
of the spindle.

Bio. Alex Mogilner is Professor of Mathematics and Biology at New York
University, with
appointments in the Courant Institute of Mathematical Sciences and the
Department of
Biology. His research lies at the interface of applied mathematics,
biophysics, and cell biology,
with current interests including cell motility, mitosis, actin dynamics,
and galvanotaxis. He
develops mathematical and computational models to understand how cells
move, divide, and
organize their internal structures, working closely with experimental cell
biologists. Before
joining NYU, he was Professor of Mathematics and Neurobiology at the
University of
California, Davis, and earlier held a Research Fellowship in the Program in
Mathematics and
Molecular Biology at the University of California, Berkeley. He has also
served on the editorial
boards of numerous journals, including Cell, Biophysical Journal, Journal
of Cell Biology,
Molecular Biology of the Cell, Current Biology, and Bulletin of
Mathematical Biology.
__________________________________________________________________________
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